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PF-06764427
产品别名
PF-06764427
1-[4-(1-Methyl-1H-pyrazol-3-yl)-benzyl]-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (3R,4S)-(3-hydroxy-tetrahydro-pyran-4-yl)-amide
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C24H25N5O3 |
Molecular weight | 431.49 |
MDL number | MFCD29037210 |
PubChem Substance ID【PubChem化学物质编号】 | 329823822 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | PF-06764427 is a selective azaindole muscarinic receptor M1 positive allosteric modulator. |
Other Notes【其他说明】 | This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
Legal Information【法律信息】 | Sold for research purposes under agreement from Pfizer Inc. Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
manufacturer/tradename | Pfizer® |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 20 mg/mL, clear |
originator【创始人】 | Pfizer |
storage temp.【储存温度】 | room temp |
SMILES string | CN1C=CC(C(C=C2)=CC=C2CN3C4=CC=CN=C4C(C(N[C@@H]5[C@@H](O)COCC5)=O)=C3)=N1 |
InChI | 1S/C24H25N5O3/c1-28-11-8-19(27-28)17-6-4-16(5-7-17)13-29-14-18(23-21(29)3-2-10-25-23)24(31)26-20-9-12-32-15-22(20)30/h2-8,10-11,14,20,22,30H,9,12-13,15H2,1H3,(H,26,31)/t20-,22-/m0/s1 |
InChI key | FQGJDGJXEZTKDW-UNMCSNQZSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS06 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H301 |
Precautionary Statements | P301 + P310 + P330 |
Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |