您的位置：首页 > 产品中心 > Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)
Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)
| 产品编号： | 3185212 |
| 规格： | average Mn (1100-1000-1100), lactide:glycolide 75:25 |
| 包装规格： | 1 G |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)
PLGA-PEG-PLGA
结构式
基本信息
| NACRES | NA.23 |
| General description【一般描述】 | PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. |
| Application【应用】 | Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs. |
| Features and Benefits【特点和优势】 | Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified. |
产品性质
| description【描述】 | typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS) |
| Quality Level【质量水平】 | 100 |
| feed ratio【投料比】 | lactide:glycolide 75:25 |
| mol wt【分子量】 | PEG average Mn 1,000 PLGA average Mn 2,200 average Mn (1100-1000-1100) |
| degradation timeframe【降解时间线】 | 2-3 weeks |
| transition temp【转变温度】 | Tm 230-235 ℃ |
| PDI | <2.0 |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 1 g in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
