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PrEST Antigen MATN1
| 产品编号： | 3199519 |
| 规格： | Prestige AntigensTM Powered by Atlas Antibodies, buffered aqueous solution |
| 包装规格： | 100 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
PrEST Antigen MATN1
CMP
CRTM
产品性质
| Quality Level【质量水平】 | 100 |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | >80% (SDS-PAGE) |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | predicted mol wt 26 kDa |
| purified by【纯化方式】 | immobilized metal affinity chromatography (IMAC) |
| concentration【浓度】 | ≥0.5 mg/mL |
| immunogen sequence【免疫原序列】 | REIASEPVAEHYFYTADFKTINQIGKKLQKKICVEEDPCACESLVKFQAKVEGLLQALTRKLEAVSKRLAILENTVV |
| Ensembl | human accession no.【基因组数据库 |人类登记号】 | ENSG00000162510 |
| UniProt accession no.【UniProt登记号】 | P21941 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MATN1(4146) |
基本信息
| General description【一般描述】 | Matrilin 1 (MATN1) is also called the cartilage matrix protein (CMP) and is the major matrix component of cartilage. The gene encoding MATN1 is mapped to human chromosome 1p35.2. Matrilin 1 (MATN1) encodes a protein of 52,000 Da and exists as trimer. It has von Willebrand factor A domain. It is a glycoprotein and interacts with cartilage collagen fibrils. |
| Application【应用】 | Suitable as a blocking agent using corresponding antibodies. |
| Biochem/physiol Actions【生化/生理作用】 | Autoantibodies to Matrilin 1 (MATN1) is implicated in patients with autoimmune disorder, polychondritis. MATN1 inhibits new capillary and blood vessel formation and could be used for treating diseases associated with improper neovascularization. Mutations in MATN1 gene impacts the assembly process of collagen. MATN1 gene polymorphisms result in spine deformity and is associated with familial idiopathic scoliosis |
| Linkage【联系】 | Corresponding Antibody HPA028580. |
| Physical form【外形】 | Solution in 1 M urea-PBS, pH 7.4 |
| Preparation Note【制备说明】 | The protein solution should be gently mixed before use. Optimal concentrations and conditions for each application should be determined by the user. |
| Legal Information【法律信息】 | Prestige Antigens is a trademark of sigma-aldrich Co. LLC |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
