丙泊酚

[(CH₃)₂CH]₂C₆H₃OH

178.27

218-206-6

MFCD00008885

329823540

NA.24

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propofol is approved for induction and maintenance of paediatric anesthesia and sedation in children less than 3 years of age. The mechanism of action involves interaction with gamma-aminobutyric acid A receptor. Rapid effect and fewer side effects like postoperative nausea makes propofol a popular intravenous anesthetic agents.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Propofol may be used as a pharmaceutical reference standard for the determination of the analyte in emulsion dosage form by sequential injection technique with spectrophotometric and fluorimetric detections.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA5999 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

300

certified reference material
pharmaceutical secondary standard

5.6 mmHg ( 100 ℃)

current certificate can be downloaded

ampule of 1 mL

HPLC: suitable
gas chromatography (GC): suitable

n20/D 1.514 (lit.)

256 ℃/764 mmHg (lit.)

18 ℃ (lit.)

0.962 g/mL at 25 ℃ (lit.)

pharmaceutical (small molecule)

neat

traceable to BP 1031
traceable to PhEur Y0000016
traceable to USP 1572503

2-8℃

CC(C)c1cccc(C(C)C)c1O

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

OLBCVFGFOZPWHH-UHFFFAOYSA-N

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

GHS07

Warning

H302 - H315 - H319 - H335

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Respiratory system

10 - Combustible liquids

WGK 3

235.4 °F - closed cup

113 ℃ - closed cup