Protein G-Biotin from Streptococcus sp.

MFCD00132111

NA.46

Protein G binds to antibodies reversibly and thus, it is considered in antibody purification. It is a 20 kDa protein.
Protein G is an immunoglobulin (IgG) specific bacterial cell wall protein isolated from Streptococci (group G). Native proteins G consist of two IgG-binding domains and albumin and cell surface binding sites. Biotin is a water soluble vitamin that acts as a coenzyme for carboxylase enzyme reactions. Biotin deficiency results in deregulation of metabolic pathways and various physiological impairments. Biotin deficiency is known to cause birth anomalies indicating its important role in development and differentiation of embryos.

Binds IgG only from most mammalian species except cat; binds chicken IgG.

Protein G-Biotin from Streptococcus sp. has been used in electrochemical biosensing, for the attachment of antibodies with different specificities.
Protein G-Biotin from Streptococcus sp. has been used during incubation for synergistic immunocapture of antigen which was performed using streptavidin-coated magnetic beads.

Truncated - lacks albumin, Fab and membrane binding sites.

Prepared using biotinamidocaproate N-hydroxysuccinimide which incorporates an aminocaproyl spacer.

200

expressed in unspecified host

biotin conjugate

lyophilized powder

Protein, ~90% biuret

2-4 mol d-biotin per mol protein

direct ELISA: 1:70,000 using human IgG

2-8℃

Package size based on protein content

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