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Protein Kinase G II from rat
| 产品编号： | 3208767 |
| 规格： | >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 cells, solution |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Protein Kinase G II from rat
Protein Kinase, 3′,5′-Cyclic GMP Dependent from rat
基本信息
| MDL number | MFCD03444648 |
| NACRES | NA.32 |
| General description【一般描述】 | Protein kinase, cGMP-dependent, type II (PRKG2), also known as type II cGMP-dependent protein kinase (cGK), is encoded by the gene mapped to human chromosome 4q13.1–q21.1. |
| Biochem/physiol Actions【生化/生理作用】 | Protein kinase, cGMP-dependent, type II (PRKG2) is implicated in the regulation of intestinal fluid balance in man. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism. |
| Unit Definition【单位定义】 | One unit will phosphorylate one μmole of VASPtide (RRKVSKQE) per minute at pH 7.4 |
产品性质
| Quality Level【质量水平】 | 200 |
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| Assay【测定】 | >90% (SDS-PAGE) |
| form【形式】 | solution |
| Specific Activity | ~0.7 U/mg |
| UniProt accession no.【UniProt登记号】 | Q64595 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | rat ... Prkg2(25523) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
