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Prothionamide
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3208833 | 1 G | 858 | |||
| 3208833 | 10 G | 4130 |
产品别名
14222-60-7
Prothionamide
2-Propylisonicotinylthioamide
2-Propylthioisonicotinamide
2-Propyl-4-pyridinecarbothioamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C9H12N2S |
| Molecular weight | 180.27 |
| MDL number | MFCD00464119 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824982 |
| NACRES | NA.85 |
| General description【一般描述】 | Prothionamide is an analogue of ethionamide, and is better tolerated and less toxic than ethionamide. It contains a propyl group instead of an ethyl group at the α position. Chemical structure: pyridine |
| Biochem/physiol Actions【生化/生理作用】 | Prothionamide is the second line of drug used in leprosy and in tuberculosis. It is highly effective against Mycobacterium tuberculosis. In patients with multidrug-resistant tuberculosis (MDR-TB), prothionamide causes the development of hepatitis. In rare cases, it causes drug reaction with eosinophilia and systemic symptoms (DRESS) in patients with MDR-TB. DRESS is characterized by fever, hematologic abnormalities, skin eruption, and internal organ disruption. |
| Other Notes【其他说明】 | Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Non Combustible Solids |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥99% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | (Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510) Non Combustible liquids.) |
| color【颜色】 | yellow |
| Mode of action【作用机制】 | enzyme | interferes |
| antibiotic activity spectrum【抗生素抗菌谱】 | mycobacteria |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | NC(C1=CC(CCC)=NC=C1)=S |
| InChI | 1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) |
| InChI key | VRDIULHPQTYCLN-UHFFFAOYSA-N |
| packaging【包装】 | 1, 10 g in poly bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
