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PYZD-4409
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3212670 | 5 MG | 1220 |
产品别名
423148-78-1
PYZD-4409
1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furanyl)methylene]-3,5-pyrazolidinedione
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H7ClFN3O5 |
| Molecular weight | 351.67 |
| MDL number | MFCD01828668 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825708 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. PYZD-4409 induces cell death, and inhbits clonogenic growth of leukemia and myeloma cell lines, and inhibits leukemia xenograft tumor growth in mice. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | , white to very dark brown |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | FC1=CC=C(N2C(C(C(N2)=O)=CC3=CC=C([N+]([O-])=O)O3)=O)C=C1Cl |
| InChI | 1S/C14H7ClFN3O5/c15-10-5-7(1-3-11(10)16)18-14(21)9(13(20)17-18)6-8-2-4-12(24-8)19(22)23/h1-6H,(H,17,20) |
| InChI key | MSYMKEYWUWVZQY-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H315 - H319 - H335 |
| Precautionary Statements | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
