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QNZ46

产品编号:3212757
规格:≥98% (HPLC)
CAS NO:1237744-13-6
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32127575 MG1710
321275725 MG4770
产品别名

1237744-13-6

QNZ46

4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)-quinazolinyl]-Benzoic acid

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C24H17N3O6
Molecular weight
443.41
MDL number
MFCD22666391
PubChem Substance ID【PubChem化学物质编号】
329825390
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
QNZ46 is a noncompetitive inhibitor of GluN2C/D containing NMDA receptors. KD and IC50 values for binding and inhibition of GluN1/Glun2D receptors by QNZ46 are 4.9 and 3.9 μM, respectively. QNZ46 does not compete for binding of glutamate or glycine, but QNZ46 receptor binding requires the binding of glutamate to the GluN2 subunit.
Features and Benefits【特点和优势】
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to beige
solubility【溶解性】
DMSO: 5 mg/mL (warmed; clear solution)
storage temp.【储存温度】
room temp
SMILES string
COc1ccc2N=C(\C=C\c3cccc(c3)[N+]([O-])=O)N(C(=O)c2c1)c4ccc(cc4)C(O)=O
InChI
1S/C24H17N3O6/c1-33-19-10-11-21-20(14-19)23(28)26(17-8-6-16(7-9-17)24(29)30)22(25-21)12-5-15-3-2-4-18(13-15)27(31)32/h2-14H,1H3,(H,29,30)/b12-5+
InChI key
GNLVJIICVWDSNI-LFYBBSHMSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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