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R-7050
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3213385 | 5 MG | 1220 | |||
3213385 | 25 MG | 4490 |
产品别名
303997-35-5
R-7050
8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
8-Chloro-4-(phenylsulfanyl)-1-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C16H8ClF3N4S |
Molecular weight | 380.77 |
MDL number | MFCD00140737 |
PubChem Substance ID【PubChem化学物质编号】 | 329825827 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | R-7050 is a cell-permeable TNF-α receptor antagonist that blocks TNF-α-induced binding of TNF-αRI with TNFαR-associated death domain protein and receptor interacting protein 1, blocking internalization of the TNFα-TNFαR complex. R-7050 was found to reduce neurovascular injury in a mouse model of hemorrhagic stroke. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | ClC1=CC=C(N=C(SC2=CC=CC=C2)C3=NN=C(C(F)(F)F)N34)C4=C1 |
InChI | 1S/C16H8ClF3N4S/c17-9-6-7-11-12(8-9)24-13(22-23-15(24)16(18,19)20)14(21-11)25-10-4-2-1-3-5-10/h1-8H |
InChI key | SUUMKHOVGVYGOP-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |