Rabbit anti-BCR Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0234 maps to a region between residue 1221 and 1271 of human breakpoint cluster region using the numbering given in entry NP_004318.3 (GeneID 613).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.

rabbit

100

affinity purified immunoglobulin

primary antibodies

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human

flow cytometry: 0.5 μg
immunofluorescence: 1:500- 1:2,000
immunoprecipitation (IP): 10 μg/mg
western blot: 1:2,000- 1:10,000

NP_004318.3

P11274

wet ice

2-8℃

rabbit ... BCR(613)

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12 - Non Combustible Liquids

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