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Rabbit anti-BLM Antibody, Affinity Purified
产品别名
Rabbit anti-BLM Antibody, Affinity Purified
Bloom syndrome
RECQ2
DNA helicase
RecQ-like type 2
RecQ helicase-like
RECQL3
BS
RECQL2
RecQ protein-like 3
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | The epitope recognized by PLA0029 maps to a region between residue 1325 and the C-terminus (residue 1417) of human Bloom Syndrome using the numbering given in entry NP_000048.1 (GeneID 641). |
| Physical form【外形】 | Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide |
| Other Notes【其他说明】 | Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| grade【等级】 | Powered by Bethyl Laboratories, Inc. |
| species reactivity | human, mouse |
| technique(s) | immunoprecipitation (IP): 2-10 μg/mg western blot: 1:1,000- 1:10,000 |
| accession no.【登记号】 | NP_000048.1 |
| UniProt accession no.【UniProt登记号】 | P54132 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| Gene Information | rabbit ... BLM(641) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
