Rabbit anti-CDK7 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0103 maps to a region between residues 300 and the C-terminus (residue 346) of human Cyclin-Dependent Kinase 7 using the numbering given in Swiss-Prot entry P50613 (GeneID 1022).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Cyclin-dependent kinase 7 (CDK7) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK7 is the catalytic subunit in a trimeric complex with cyclin H and MAT1 that functions as a Cdk-activating kinase (CAK). CDK7 activates the kinase activities of CDK1, CDK2, CDK4, and CDK6 by threonine phosphorylation. In addition to its cell cycle function CDK7 has also been found to be an essential component of the transcription factor TFIIH. Several substrates of CDK7 are involved in transcription, further indicating a role in transcription.

rabbit

100

affinity purified immunoglobulin

primary antibodies

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mouse, human, rat

immunohistochemistry: 1:100-1:500
immunohistochemistry: 1:500-1:2,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000

P50613

P50613

wet ice

2-8℃

rabbit ... CDK7(1022)

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12 - Non Combustible Liquids

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