Rabbit anti-Cul1 Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0277 maps to a region between residue 726 and 776 of human Cullin 1 using the numbering given in entry NP_003583.2 (GeneID 8454).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13616]

rabbit

100

affinity purified immunoglobulin

primary antibodies

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mouse, human

immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000

NP_003583.2

Q13616

wet ice

2-8℃

rabbit ... Cul1(8454)

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12 - Non Combustible Liquids

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