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Salsalate

产品编号:3216615
规格:≥98% (HPLC)
CAS NO:552-94-3
包装规格:50 MG,250 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
321661550 MG1660
3216615250 MG5770
产品别名

552-94-3

Salsalate

2-Hydroxybenzoic acid 2-carboxyphenyl ester

salicyloxysalicylic acid

disalicylic acid

2-(2-Hydroxybenzoyl)oxybenzoic acid

Salicylsalicylic acid

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H10O5
Molecular weight
258.23
EC number【EC 号】
209-027-4
MDL number
MFCD00020252
PubChem Substance ID【PubChem化学物质编号】
329825134
NACRES
NA.77
Application【应用】
Salsalate was used to study the effect on palmitate-induced insulin resistance and hepatic steatosis in obese rats.
Biochem/physiol Actions【生化/生理作用】
Salsalate is a nonsteroidal anti-inflammatory drug (NSAID), a nonacetylated salicylate with no more problems of gastrointestinal bleeding than placebo. It inhibits synthesis and release of prostaglandins through the inactivation of cyclooxygenase-1 (COX-1) and COX-2. Salsalate is currently being investigated as a treatment for Type 2 diabetes with possible use to prevent the disease in people at risk. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to tan
solubility【溶解性】
DMSO: ≥15 mg/mL
storage temp.【储存温度】
room temp
SMILES string
OC(=O)c1ccccc1OC(=O)c2ccccc2O
InChI
1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17)
InChI key
WVYADZUPLLSGPU-UHFFFAOYSA-N
packaging【包装】
50, 250 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07,GHS09
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H400
Precautionary Statements
P273 - P301 + P312 + P330
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Aquatic Acute 1
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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