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SB-269970 hydrochloride
| 产品编号： | 3217001 |
| 规格： | powder, ≥98% (HPLC) |
| CAS NO： | 261901-57-9 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3217001 | 5 MG | 4260 | |||
| 3217001 | 25 MG | 11990 |
产品别名
261901-57-9
SB-269970 hydrochloride
(R)-3-[2-[2-(4-Methylpiperidin-1-yl)ethyl]pyrrolidine-1-sulfonyl]phenol hydrochloride
SB 269970A
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H28N2O3S · HCl |
| Molecular weight | 388.95 |
| MDL number | MFCD03788020 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278708 |
| NACRES | NA.77 |
| Application【应用】 | SB-269970 hydrochloride has been used to study the effect of different endotype combination on the activity of the 5-hydroxytryptamine receptor of tall fescue alkaloids. It has also been used to inhibit dopamine receptor signaling, in order to study its role in early hemocyte activation. SB-269970 was used to study the role of 5-HT7 receptors in serotonin-induced hypothermia in rodents.6 |
| Biochem/physiol Actions【生化/生理作用】 | SB-269970 is an anti-psychotic agent that shows high affinity for 5-HT7 receptors. It may be effective in treating cognitive disabilities and schizophrenia-like deficits.4 SB-269970 desensitizes and decreases the excitatory effects of 5-HT7 receptors in rat hippocampus.5 Selective 5-HT7 serotonin receptor antagonist. |
| Legal Information【法律信息】 | Sold with the permission of GlaxoSmithKline Pharmaceuticals |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D 75 to 90°, c = 1.0 in DMSO |
| storage condition【储存条件】 | desiccated |
| solubility【溶解性】 | H2O: 10 mg/mL, clear (warmed to 60 ℃) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.CC1CCN(CC1)CC[C@H]2CCCN2S(=O)(=O)c3cccc(O)c3 |
| InChI | 1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18;/h2,5-6,14-16,21H,3-4,7-13H2,1H3;1H/t16-;/m1./s1 |
| InChI key | XQCJOYZLWFNDIO-PKLMIRHRSA-N |
| Gene Information | human ... HTR7(3363) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
