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SB-590885
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3217011 | 5 MG | 2090 | |||
| 3217011 | 25 MG | 6180 |
产品别名
405554-55-4
SB-590885
5-(2-(4-(2-Dimethylaminoethoxy)phenyl)-5-(4-pyridinyl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H27N5O2 |
| Molecular weight | 453.54 |
| MDL number | MFCD16038645 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825450 |
| Application【应用】 | SB-590885 has been used as a component of a mixture to maintain naive human pluripotent stem cells (PSCs).It has also been used as B-Raf (BRAF) inhibitor to study its effects on lung adenocarcinoma cell lines. |
| Biochem/physiol Actions【生化/生理作用】 | SB-590885 is a potent and selective ATP competitive inhibitor of B-Raf kinase with Kd = 300 pM for B-Raf, and >1000-fold selectivity over a panel of 22 commonly studied cellular kinases |
| Features and Benefits【特点和优势】 | This compound is featured on the MAPKKKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL (clear solution, warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN(C)CCOc1ccc(cc1)-c2nc(-c3ccc4c(CC\C4=N\O)c3)c([nH]2)-c5ccncc5 |
| InChI | 1S/C27H27N5O2/c1-32(2)15-16-34-22-7-3-19(4-8-22)27-29-25(18-11-13-28-14-12-18)26(30-27)21-5-9-23-20(17-21)6-10-24(23)31-33/h3-5,7-9,11-14,17,33H,6,10,15-16H2,1-2H3,(H,29,30)/b31-24- |
| InChI key | MLSAQOINCGAULQ-QLTSDVKISA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
