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[6]-姜烯酚

Shogaol
产品编号:3218494
规格:≥90% (HPLC)
CAS NO:555-66-8
包装规格:50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
321849450 MG9200
产品别名

555-66-8

[6]-姜烯酚

Shogaol

[6]-Shogaol

(6)-Shogaol

1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one

1-(4-羟基-3-甲氧基苯基)癸-4-烯-3-酮

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C17H24O3
Molecular weight
276.37
Beilstein
2056098
MDL number
MFCD01736094
PubChem Substance ID【PubChem化学物质编号】
329824943
NACRES
NA.25
General description【一般描述】
Shogaol or 6-shogaol, the pungent metabolite of dried ginger, is one of the main bioactive compounds extracted from the natural dietary rhizome, Zingiber officinale Roscoe (ginger). It is the dehydrated successor of 6-gingerol with an α,β-unsaturated ketone skeleton.
Application【应用】
Shogaol has been used to determine its safe dose to evaluate potential toxicity in higher concentrations in mice models. It has also been used to investigate its antioxidant effects on the modulation of TRPC5 (ITRPC5) and TRPA1 (ITRPA1) currents.
Biochem/physiol Actions【生化/生理作用】
Shogaols exhibits higher potency, efficacy, and biological activities than gingerols. It is an excellent antioxidant agent, that protects human primary epidermal melanocytes against oxidative stress by activating nuclear factor E2-related factor (Nrf2)-antioxidant response. Shogaol also displays antimicrobial, antifungal, and anti-biofilm activities against Candida albicans, and Candida auris. It exerts anti-inflammatory properties and protects against abdomen irradiation (ABI)-induced intestinal side effects. 6-shogaol also inhibits lipopolysaccharide (LPS)-induced inflammation via peroxisome proliferator-activated receptor gamma (PPAR-γ) activation.
产品性质
Assay【测定】
≥90% (HPLC)
form【形式】
liquid
storage temp.【储存温度】
2-8℃
SMILES string
CCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
InChI
1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+
InChI key
OQWKEEOHDMUXEO-BQYQJAHWSA-N
packaging【包装】
50 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302
Hazard Classifications【危险分类】
Acute Tox. 4 Oral
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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