SQ109

产品编号：

3242736

规格：	≥98% (HPLC)

CAS NO：

包装规格：

10 MG，50 MG

产品类别：

进口试剂

品牌：	Sigma-Aldrich

优惠价：

产品价格

产品别名

502487-67-4

SQ109

N-[(2E)-3,7-Dimethyl-2,6-octadienyl]-N′-tricyclo[3.3.1.13,7]dec-2-yl-1,2-ethanediamine

N-[(2E)-3,7-dimethyl-2,6-octadienyl]-NOE-tricyclo[3.3.1.13,7]dec-2-yl-1,2-ethanediamine

NSC 722041

结构式

基本信息

Empirical Formula【经验(实验)分子式】	C₂₂H₃₈N₂
Molecular weight	330.55
PubChem Substance ID【PubChem化学物质编号】	329825775
NACRES	NA.77
General description【一般描述】	SQ109 is a 1,2-ethylenediamine, which is related to ethambutol.
Application【应用】	SQ109 has been used: as an antitubercular agent to study its interactions with mycobacterial membrane proteins large 3 (MmpL3) binding pocket as a positive control to determine the minimum inhibitory concentration (MIC) of ohmyungsamycins (OMS) A and B against Mycobacterium tuberculosis (Mtb) using the resazurin microtiter assay (REMA) plate method as an inhibitor of MmpL3 to explore the utility of mycobacterial CRISPR interference for validating target gene essentiality and compound mode of action
Biochem/physiol Actions【生化/生理作用】	SQ109 exhibits activity against Helicobacter pylori and the fungi Candida albicans. It might also possess anti-bacterial activity. SQ109 is an antitubercular developed for the treatment of multidrug-resistant tuberculosis (MDR-TB). SQ109 inhibits the activity of MmpL3, a mycolic acid transporter required for incorporation of mycolic acid into the Mycobacterium tuberculosis cell wall.

产品性质

Quality Level【质量水平】	100
Assay【测定】	≥98% (HPLC)
form【形式】	oil
color【颜色】	colorless to yellow
storage temp.【储存温度】	2-8℃
SMILES string	C/C(CCC=C(C)C)=C\CNCCNC1[C@@H]2C[C@@H]3C[C@H]1C[C@H](C2)C3
InChI	1S/C22H38N2/c1-16(2)5-4-6-17(3)7-8-23-9-10-24-22-20-12-18-11-19(14-20)15-21(22)13-18/h5,7,18-24H,4,6,8-15H2,1-3H3/b17-7+
InChI key	JFIBVDBTCDTBRH-REZTVBANSA-N

安全信息

Storage Class Code【储存分类代码】	13 - Non Combustible Solids
WGK	WGK 3

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