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SR-46349 hemifumarate salt
产品别名
130580-02-8
SR-46349 hemifumarate salt
SR-46349B
4-((3Z)-3-(2-Dimethylaminoethyl)oxyimino-3-(2-fluorophenyl)propen-1-yl)phenol hemifumarate salt
Eplivanserin hemifumarate salt
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H21FN2O2 · 0.5 C4H4O4 |
| Molecular weight | 386.42 |
| MDL number | MFCD12546335 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824579 |
| NACRES | NA.77 |
| Application【应用】 | SR-46349 hemifumarate salt may be used in cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | SR-46349 is an antagonist of 5-HT (2A/2C) receptor and increases the release of dopamine by medial prefrontal cortex in rats.1 It increases the signal transduction induced by 5-HT2 receptor by binding with high affinity.2 SR-46349 inhibits the aggregation of rabbit and human platelets in response to serotonin.3 ASTAR (Antagonist of Serotonin 5HT2A Receptors). |
| Features and Benefits【特点和优势】 | This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: ≥10 mg/mL |
| originator【创始人】 | Sanofi Aventis |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC(=O)\C=C\C(O)=O.CN(C)CCO\N=C(\C=C\c1ccc(O)cc1)c2ccccc2F.CN(C)CCO\N=C(\C=C\c3ccc(O)cc3)c4ccccc4F |
| InChI | 1S/2C19H21FN2O2.C4H4O4/c2*1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15;5-3(6)1-2-4(7)8/h2*3-12,23H,13-14H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b2*12-9+,21-19-;2-1+ |
| InChI key | RNLKLYQQDLHHBH-ABDBJYMXSA-N |
| Gene Information | human ... HTR2A(3356) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H410 |
| Precautionary Statements | P273 - P501 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
