您的位置：首页 > 产品中心 > 3424-98-4， Telbivudine
Telbivudine
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3248985 | 5 MG | 1420 | |||
| 3248985 | 25 MG | 6170 |
产品别名
3424-98-4
Telbivudine
Epavudine
1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-Pyrimidinedione
Sebivo
2′-Deoxy-L-thymidine
NV 02B
L-Thymidine
β-L-Thymidine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H14N2O5 |
| Molecular weight | 242.23 |
| MDL number | MFCD02683612 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825300 |
| NACRES | NA.77 |
| Application【应用】 | Telbivudine has been used to explore the mechanisms of telbivudine (LdT) induced creatine kinase (CK) elevation. |
| Biochem/physiol Actions【生化/生理作用】 | Telbivudine is a nucleoside analog that is widely used to treat hepatitis B virus (HBV) infection. Telbivudine is a synthetic molecule containing β-L-configuration. Telbivudine improves the estimated glomerular filtration rate (eGFR) in response to chronic hepatitis B (CHB). It prevents perinatal transmission and enhances the hepatitis B e antigen (HBeAg) seroconversion. It is also known to cause side effects such as creatine kinase (CK) elevation and fatal rhabdomyolysis. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D -15 to -22°, c = 1 in H2O |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 10 mg/mL (clear solution) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O |
| InChI | 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1 |
| InChI key | IQFYYKKMVGJFEH-CSMHCCOUSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
