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Terodiline hydrochloride
产品别名
7082-21-5
Terodiline hydrochloride
Bicor
N-(1,1-Dimethylethyl)-alpha-methyl-gamma-phenylbenzenepropamine hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H27N·HCl |
| Molecular weight | 317.90 |
| MDL number | MFCD00941402 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826797 |
| Biochem/physiol Actions【生化/生理作用】 | Terodiline hydrochloride is a non-selective calcium channel antagonist with anticholinergic and vasodilatory activity. Terodiline is known to increase corrected QT interval (QTc) and decrease resting heart rate in elderly patients. Furthermore, terodiline hydrochloride has been linked to cardiac arrhythmias1. |
| Features and Benefits【特点和优势】 | This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
| Preparation Note【制备说明】 | Terodiline hydrochloride is soluble in DMSO at a concentration that is greater than 20 mg/ml. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | Cl.CC(CC(c1ccccc1)c2ccccc2)NC(C)(C)C |
| InChI | 1S/C20H27N.ClH/c1-16(21-20(2,3)4)15-19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5-14,16,19,21H,15H2,1-4H3;1H |
| InChI key | RNGHAJVBYQPLAZ-UHFFFAOYSA-N |
| Gene Information | human ... CACNA1A(773), CACNA1B(774), CACNA1C(775), CACNA1D(776), CACNA1E(777), CACNA1F(778), CACNA1G(8913), CACNA1H(8912), CACNA1I(8911), CACNA1S(779), CACNA2D1(781), CACNA2D2(9254), CACNA2D3(55799), CACNA2D4(93589), CACNB1(782), CACNB2(783), CACNB3(784), CACNB4(785), CACNG1(786), CACNG2(10369), CACNG3(10368), CACNG4(27092), CACNG5(27091), CACNG6(59285), CACNG7(59284), CACNG8(59283), CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H319 - H400 |
| Precautionary Statements | P273 - P301 + P312 + P330 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
