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Thymidine Phosphorylase, recombinant from Escherichia coli

产品编号:3251976
规格:recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500 units/mL
CAS NO:9030-23-3
包装规格:5000 UNITS
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
32519765000 UNITS8650
产品别名

9030-23-3

Thymidine Phosphorylase, recombinant from Escherichia coli

Thymidine:orthophosphate deoxy-D-ribosyltransferase

基本信息
Enzyme Commission (EC) Number【酶学委员会(EC)编号】
2.4.2.4 ( BRENDA | IUBMB )
MDL number
MFCD00132426
NACRES
NA.54
Biochem/physiol Actions【生化/生理作用】
An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.
Unit Definition【单位定义】
One unit will convert 1.0 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per min at pH 7.4 at 25℃.
Preparation Note【制备说明】
Cloned from E. coli and produced in overexpressing E. coli
产品性质
recombinant【重组】
expressed in E. coli
Quality Level【质量水平】
400
form【形式】
buffered aqueous solution
concentration【浓度】
≥500 units/mL
application(s)
diagnostic assay manufacturing
shipped in【运输】
wet ice
storage temp.【储存温度】
2-8℃
packaging【包装】
5000 units in glass bottle
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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