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Trandolapril
| 产品编号： | 3253910 |
| 规格： | ≥98% (HPLC), white, powder |
| CAS NO： | 87679-37-6 |
| 包装规格： | 10 MG，50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3253910 | 10 MG | 2360 | |||
| 3253910 | 50 MG | 6850 |
产品别名
87679-37-6
群多普利
Trandolapril
(2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid
Mavik
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H34N2O5 |
| Molecular weight | 430.54 |
| MDL number | MFCD00865776 |
| PubChem Substance ID【PubChem化学物质编号】 | 329826801 |
| NACRES | NA.77 |
| Application【应用】 | Trandolapril has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on responsiveness of human retinal endothelial cells (HRECs) to vascular endothelial growth factor (VEGF). |
| Biochem/physiol Actions【生化/生理作用】 | Trandolapril is an ACE inhibitor. Trandolapril differs from other ACE inhibitors in that it has a longer biological half-life and a high degree of lipophilicity. Studies have reported that trandolapril inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2. |
| Features and Benefits【特点和优势】 | This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Preparation Note【制备说明】 | Trandolapril is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml. |
| Other Notes【其他说明】 | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T4827.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: ≥20 mg/mL |
| originator【创始人】 | Abbott |
| SMILES string | CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C3CCCCC3C[C@H]2C(O)=O |
| InChI | 1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1 |
| InChI key | VXFJYXUZANRPDJ-WTNASJBWSA-N |
| Gene Information | human ... ACE(1636) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H360D |
| Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Classifications【危险分类】 | Repr. 1B |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
