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Trequinsin hydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3254592 | 10 MG | 3670 |
产品别名
78416-81-6
Trequinsin hydrochloride
HL 725
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H27N3O3 · HCl |
| Molecular weight | 441.95 |
| MDL number | MFCD01076563 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278727 |
| NACRES | NA.77 |
| Application【应用】 | Trequinsin has been used as a PDE3 inhibitor in rat juxtaglomerular cells. This study reported that trequinsin can enhance cellular cAMP content, forskolin-induced cAMP synthesis, and renin release in cells. |
| Biochem/physiol Actions【生化/生理作用】 | Trequinsin is a strong antihypertensive agent that has a hemodynamic profile similar to that of arteriolar dilators. Trequinsin can block platelet aggregation and also inhibit tissue factor expression in human endothelial cells,. Phosphodiesterase III inhibitor. |
| Features and Benefits【特点和优势】 | This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% |
| form【形式】 | powder |
| SMILES string | Cl[H].COc1cc2CCN3C(=O)N(C)C(\C=C3c2cc1OC)=N\c4c(C)cc(C)cc4C |
| InChI | 1S/C24H27N3O3.ClH/c1-14-9-15(2)23(16(3)10-14)25-22-13-19-18-12-21(30-6)20(29-5)11-17(18)7-8-27(19)24(28)26(22)4;/h9-13H,7-8H2,1-6H3;1H/b25-22+; |
| InChI key | DTCZZBVPTHVXFA-OSMRDGEFSA-N |
| Gene Information | human ... PDE3A(5139), PDE3B(5140) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
