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TRO 19622
| 产品编号： | 3256298 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 22033-87-0 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
22033-87-0
TRO 19622
Cholest-4-en-3-one, oxime
NSC 21311
Olesoxime
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H45NO |
| Molecular weight | 399.65 |
| NACRES | NA.77 |
| Application【应用】 | TRO 19622 has been used as a mitochondrial permeability transition pore inhibitor in mouse neurons2. TRO 19622 is also known to stimulate myelin repair in rat models of demyelination3. |
| Biochem/physiol Actions【生化/生理作用】 | TRO 19622 can decrease axonal degradation and enhance the rescue of motor nerve conduction in peripheral neuropathy. Furthermore, TRO 19622 can reverse neuropathic pain and tactile allodynia in rat models of diabetes and chemotherapy-induced neuropathic pain4. TRO19622 ia a neuroprotective agent for motor neurons; candidate therapeutic for amyotrophic lateral sclerosis (ALS). |
| Preparation Note【制备说明】 | TRO 19622 is soluble in DMSO at a concentration that is greater than 10 mg/ml. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C27H45NO/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28-29)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25,29H,6-16H2,1-5H3/b28-21+ |
| InChI key | QNTASHOAVRSLMD-SGWCAAJKSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
