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TVP1022
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3257471 | 5 MG | 1430 | |||
| 3257471 | 25 MG | 5250 |
产品别名
185517-74-2
TVP1022
(S)-Rasagiline
S-(-)-N-Propargyl-1-aminoindan
(1S)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C12H13N |
| Molecular weight | 171.24 |
| MDL number | MFCD09029306 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825241 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | TVP1022, the S-isomer of rasagiline, an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. TVP1022, a neuroprotective and cytoprotective molecule, is also cardioprotective in rat models. Its activity is believed to involve stabilization of mitochondrial membrane potential, induction of Bcl-2 and activation of the PKC signalling pathway, enhancing the phosphorylation of protein kinase C and glycogen synthase kinase-3β. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| solubility【溶解性】 | DMSO: ≥15 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | C#CCN[C@H]1CCc2ccccc12 |
| InChI | 1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m0/s1 |
| InChI key | RUOKEQAAGRXIBM-LBPRGKRZSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H400 |
| Precautionary Statements | P273 - P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Aquatic Acute 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
