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VAHA
产品别名
106132-78-9
VAHA
Valproyl hydroxamic acid, VPA-HA
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C8H17NO2 |
| Molecular weight | 159.23 |
| MDL number | MFCD12756348 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825087 |
| NACRES | NA.77 |
| Application【应用】 | VAHA may be used in cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. It is effective in the treatment of bipolar disorders. VAHA (Valproyl hydroxamic acid) is an HDAC inhibitor with less activity than valproic acid against Class I enzymes but much greater Class II activity |
| Features and Benefits【特点和优势】 | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| solubility【溶解性】 | DMSO: ≥25 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCCC(CCC)C(=O)NO |
| InChI | 1S/C8H17NO2/c1-3-5-7(6-4-2)8(10)9-11/h7,11H,3-6H2,1-2H3,(H,9,10) |
| InChI key | ROJGIRXXBBBMPL-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
