伐地昔布

C₁₆H₁₄N₂O₃S

314.36

MFCD00950568

329823753

NA.77

Valdecoxib (VCX) is a diaryl substituted isoxazole compound. It comprises of sulfonyl propanamide and is a metabolite of parecoxib.

Valdecoxib may be used: as cyclooxygenase-2 (COX-2) inhibitor in fibroblast cells, as an analyte for mass spectrometry analysis, as an standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for quantification of valdecoxib in plasma samples

Valdecoxib is reported to elicit anti-inflammatory, analgesic and antipyretic functionality. It acts as a substrate for the liver enzyme cytochrome P450 2C9(CYP2C9) and cytochrome P450 3A4 (CYP3A4).
Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase-2 (COX-2) selective inhibitor.

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

100

≥98% (HPLC)

powder

Pfizer^®

white to off-white

DMSO: >25 mg/mL

Pfizer

room temp

Cc1onc(-c2ccccc2)c1-c3ccc(cc3)S(N)(=O)=O

1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20)

LNPDTQAFDNKSHK-UHFFFAOYSA-N

human ... PTGS2(5743)

5, 25 mg in glass bottle

GHS08,GHS09

Warning

H361d - H373 - H410

P201 - P202 - P260 - P273 - P280 - P308 + P313

Aquatic Chronic 1 - Repr. 2 - STOT RE 2

11 - Combustible Solids

WGK 3