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羟钴胺 盐酸盐
Vitamin B12a hydrochloride
产品编号: | 3258930 |
规格: | ≥96% (UV), ≥96% (HPLC) |
CAS NO: | 59461-30-2 |
包装规格: | 250 MG,1 G |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3258930 | 250 MG | 959 | |||
3258930 | 1 G | 3220 |
产品别名
59461-30-2
羟钴胺 盐酸盐
Vitamin B12a hydrochloride
Hydroxocobalamin hydrochloride
维生素 B 12a
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C62H89CoN13O15P · HCl |
Molecular weight | 1382.82 |
EC number【EC 号】 | 261-772-4 |
MDL number | MFCD00167463 |
PubChem Substance ID【PubChem化学物质编号】 | 57653658 |
NACRES | NA.79 |
Application【应用】 | Vitamin B12a hydrochloride has been used as an antidote for cyanide poisoning. |
Biochem/physiol Actions【生化/生理作用】 | Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine. |
Other Notes【其他说明】 | Review |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | fermentation/recombinant |
Assay【测定】 | ≥96% (HPLC) ≥96% (UV) |
form【形式】 | powder or crystals |
loss【缺失】 | ≤12% loss on drying, 20 ℃ (HV) |
color【颜色】 | red to dark red |
solubility【溶解性】 | methanol: 10 mg/mL at 20 ℃, clear, dark red |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | Cl.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N([Co+]O)C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78 |
InChI | 1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;;/m1.../s1 |
InChI key | KEHNCSYXYMMUCO-BXSGNKEGSA-K |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |