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羟钴胺 盐酸盐

Vitamin B12a hydrochloride
产品编号:3258930
规格:≥96% (UV), ≥96% (HPLC)
CAS NO:59461-30-2
包装规格:250 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3258930250 MG959
32589301 G3220
产品别名

59461-30-2

羟钴胺 盐酸盐

Vitamin B12a hydrochloride

Hydroxocobalamin hydrochloride

维生素 B 12a

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C62H89CoN13O15P · HCl
Molecular weight
1382.82
EC number【EC 号】
261-772-4
MDL number
MFCD00167463
PubChem Substance ID【PubChem化学物质编号】
57653658
NACRES
NA.79
Application【应用】
Vitamin B12a hydrochloride has been used as an antidote for cyanide poisoning.
Biochem/physiol Actions【生化/生理作用】
Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms. Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.
Other Notes【其他说明】
Review
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
fermentation/recombinant
Assay【测定】
≥96% (HPLC)
≥96% (UV)
form【形式】
powder or crystals
loss【缺失】
≤12% loss on drying, 20 ℃ (HV)
color【颜色】
red to dark red
solubility【溶解性】
methanol: 10 mg/mL at 20 ℃, clear, dark red
storage temp.【储存温度】
2-8℃
SMILES string
Cl.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)[C@H]2N([Co+]O)C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@H]6[C@@H](O)[C@H](O[C@@H]6CO)n7cnc8cc(C)c(C)cc78
InChI
1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;;/m1.../s1
InChI key
KEHNCSYXYMMUCO-BXSGNKEGSA-K
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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