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VPC-14228
产品别名
19983-28-9
VPC-14228
4-(4-Phenylthiazol-2-yl)morpholine
2-Morpholino-4-phenylthiazole
4-(4-Phenyl-2-thiazolyl)-morpholine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H14N2OS |
| Molecular weight | 246.33 |
| MDL number | MFCD00628805 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825954 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | VPC-14228 is a potent and specific inhibitor of human androgen receptor (AR) that binds to AR DNA-binding domain (AR DBD). Apparently VPC-14228 blocks the transcriptional activity of constitutively active AR splice variants. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | C1(N2CCOCC2)=NC(C3=CC=CC=C3)=CS1 |
| InChI | 1S/C13H14N2OS/c1-2-4-11(5-3-1)12-10-17-13(14-12)15-6-8-16-9-7-15/h1-5,10H,6-9H2 |
| InChI key | MRNNJVNMXOZEQC-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H319 |
| Precautionary Statements | P301 + P312 + P330 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
