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VU591
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3259240 | 5 MG | 1650 | |||
| 3259240 | 25 MG | 4860 |
产品别名
1222810-74-3
VU591
2,2′-(oxydimethanediyl)bis(6-nitro-1H-benzimidazole)
5-nitro-2-{[(6-nitro-1H-benzimidazol-2-yl)methoxy]methyl}-1H-benzimidazole
2,2′-(oxydimethanediyl)bis(5-nitro-1H-benzimidazole)
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H12N6O5 |
| Molecular weight | 368.30 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825139 |
| NACRES | NA.77 |
| Application【应用】 | VU591 may be used in cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK) specific inhibitor (IC50 = 240 nM) that is closely related to VU590. Unlike VU590, VU591 does not inhibit Kir7.1. The compound has a modest effect on Kir6.2/SUR1, causing 17% inhibition at 10 uM. |
| Features and Benefits【特点和优势】 | This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥12 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | [O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1 |
| InChI | 1S/C16H12N6O5/c23-21(24)9-1-3-11-13(5-9)19-15(17-11)7-27-8-16-18-12-4-2-10(22(25)26)6-14(12)20-16/h1-6H,7-8H2,(H,17,19)(H,18,20) |
| InChI key | ZQPXNYLXYNRFNP-UHFFFAOYSA-N |
| Gene Information | human ... KCNJ1(3758) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
