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2-氯-2,2-二氟苯乙酮

2-Chloro-2,2-difluoroacetophenone
产品编号:3274202
规格:95%
CAS NO:384-67-8
包装规格:10 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
327420210 G2080
产品别名

384-67-8

2-氯-2,2-二氟苯乙酮

2-Chloro-2,2-difluoroacetophenone

α-Chloro-α,α-difluoroacetophenone

2-Chloro-2,2-difluoro-1-phenylethanone

Chlorodifluoromethyl phenyl ketone

结构式
基本信息
Linear Formula【线性分子式】
C6H5COCF2Cl
Molecular weight
190.57
Beilstein
2251448
MDL number
MFCD00042123
PubChem Substance ID【PubChem化学物质编号】
329768330
General description【一般描述】
2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, and gem -difluoromethene derived compounds.
Application【应用】
2-Chloro-2,2-difluoroacetophenone can be used:
  • As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.
  • As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.
  • As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.


Reagent is an effective product for the synthesis of difluoromethylated phenols in the presence of mild base and aqueous solvent.
产品性质
Quality Level【质量水平】
100
Assay【测定】
95%
refractive index【折射率】
n20/D 1.4954
n20/D 1.497 (lit.)
bp
94-96 ℃/35 mmHg (lit.)
density
1.293 g/mL at 25 ℃ (lit.)
1.3178 g/mL at 25 ℃
SMILES string
FC(F)(Cl)C(=O)c1ccccc1
InChI
1S/C8H5ClF2O/c9-8(10,11)7(12)6-4-2-1-3-5-6/h1-5H
InChI key
MNOONJNILVDLSW-UHFFFAOYSA-N
packaging【包装】
1, 10 g in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)【闪点(F)】
160.0 °F
Flash Point(C)【闪点(C)】
71.1 ℃
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