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2OHOA
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3282948 | 5 MG | 1390 | |||
3282948 | 25 MG | 4930 |
产品别名
56472-29-8
2OHOA
(9Z)-2-Hydroxy-9-octadecenoic acid; cis-2-Hydroxy-9-octadecenoic acid
2-Hydroxy Oleic Acid
Minerval
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H34O3 |
Molecular weight | 298.46 |
MDL number | MFCD07778553 |
PubChem Substance ID【PubChem化学物质编号】 | 329825264 |
NACRES | NA.77 |
Application【应用】 | 2OHOA has been used as:
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Biochem/physiol Actions【生化/生理作用】 | 2-Hydroxy oleic acid (2OHOA) is a derivative of oleic acid. It plays a role in membrane organization, alterations in membrane fluidity, an increase of the tendency to form non-lamellar structures, and remodeling of microdomains by interacting with the lipids in membranes of pathological cells. 2OHOA induces cell cycle arrest and apoptosis in several cancer cell lines, including glioma, leukemia, breast and colon cancer lines. 2OHOA increases sphingomyelin (SM) levels in the membranes of tumor cells, which typically display decreased SM membrane content, and remodeled membranes, compared with normal cells. The compound has no effect on SM levels in non-cancer cells. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
storage condition【储存条件】 | protect from light |
color【颜色】 | white to tan |
solubility【溶解性】 | DMSO: >20 mg/mL |
storage temp.【储存温度】 | room temp |
SMILES string | CCCCCCCC\C=C/CCCCCCC(O)C(O)=O |
InChI | 1S/C18H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(19)18(20)21/h9-10,17,19H,2-8,11-16H2,1H3,(H,20,21)/b10-9- |
InChI key | JBSOOFITVPOOSY-KTKRTIGZSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS05 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H318 |
Precautionary Statements | P280 - P305 + P351 + P338 |
Hazard Classifications【危险分类】 | Eye Dam. 1 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |