3-氰基色酮

C₁₀H₅NO₂

171.15

MFCD00052604

24863972

NA.22

3-Cyanochromone (4-Oxo-4H-1-benzopyran-3-carbonitrile), a 3-substituted chromone, is a cyano substituted 1-benzopyran-4-one. It is an α,β-unsaturated nitrile and also an α,β-unsaturated ketone. Its molecule has electron deficiency at 3 sites i.e C (carbon) at second position, C of cyano and carbonyl group. 2-Amino-3-(alkyliminomethyl)chromones are obtained as major products during its reaction with aliphatic amines.

3-Cyanochromone may be used in the syntheses of following:

• 2-aminochromone-3-carboxamide
• 3-amino-4H-chromeno[3,4-d]isoxazol-4-one
• 3-(diaminomethylene)chroman-2,4-dione
• functionalized novel spirobenzofuranones
• 6H-bis-[1]-benzopyrano[2,3-b:3′,4′-e]pyridin-8(8H)ones and 3-(2′-hydroxybenzoyl)-5H-[1]benzopyrano[4,3-b]pyridine

100

97%

174-176 ℃ (lit.)

O=C1C(=COc2ccccc12)C#N

1S/C10H5NO2/c11-5-7-6-13-9-4-2-1-3-8(9)10(7)12/h1-4,6H

SFWNPLLGXKJESA-UHFFFAOYSA-N

5, 25 g in glass bottle

GHS06

Danger

H301 - H312 + H332

P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK 3