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5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt

产品编号:3325281
规格:~85%
CAS NO:103226-10-4
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
33252815 MG3040
332528125 MG11640
产品别名

103226-10-4

5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt

FdUMP

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C9H12FN2O8P
Molecular weight
326.17
MDL number
MFCD00057409
PubChem Substance ID【PubChem化学物质编号】
24894845
NACRES
NA.51
Application【应用】
5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt has been used as an anti-mitotic agent and is used extensively in studies on the activity and function of thymidylate synthase (TS).
Biochem/physiol Actions【生化/生理作用】
5-Fluoro-2′-deoxyuridine 5′-monophosphate sodium salt (FdUMP) is an DNA synthesis inhibitor. FdUMP along with RNA synthesis inhibitor 3′-C-ethinylcytidine induces cell death in cervical cancer cells at nanomolar concentrations.
产品性质
Quality Level【质量水平】
200
Assay【测定】
~85%
form【形式】
solid
storage temp.【储存温度】
−20℃
SMILES string
[Na].OC1CC(OC1COP(O)(O)=O)N2C=C(F)C(=O)NC2=O
InChI
1S/C9H12FN2O8P.Na.H/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(20-7)3-19-21(16,17)18;;/h2,5-7,13H,1,3H2,(H,11,14,15)(H2,16,17,18);;
InChI key
DGEOOGBABXVZPJ-UHFFFAOYSA-N
packaging【包装】
5 mg in glass bottle
25 mg in poly bottle
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H302 + H312 + H332 - H351
Precautionary Statements
P201 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
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