5-Methoxy-1,2,3-triazine

C₄H₅N₃O

111.10

329772693

NA.22

5-Methoxy-1,2,3-triazine is a 1,2,3-triazine derivative bearing electron-donating substituent. It participates in the inverse electron demand Diels-Alder reactions. 5-Methoxy-1,2,3-triazine readily reacts with amidines. It can be prepared from 4-methoxypyrazole.

5-Methoxy-1,2,3-triazine may be used in the synthesis of nitrogen-containing heterocyclic compounds.
1, 2, 3-Triazines have shown to be reactive substrates in inverse electron demand Diels-Alder strategies. Recent examples by Boger and coworkers utilize this reactive motif in the construction of highly functionalized N-containing heterocycles.

Cycloadditions of 1,2,3-Triazines Bearing C5-Electron Donating Substituents: Robust Pyrimidine Synthesis

powder

100

2-8℃

COC1=CN=NN=C1

1S/C4H5N3O/c1-8-4-2-5-7-6-3-4/h2-3H,1H3

HVBZCUMRMKODNE-UHFFFAOYSA-N

13 - Non Combustible Solids

WGK 3