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6-Methylmercaptopurine riboside
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3331125 | 1 G | 4050 |
产品别名
342-69-8
6-Methylmercaptopurine riboside
6-(Methylthio)-9-β-
6MMPr
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H14N4O4S |
| Molecular weight | 298.32 |
| EC number【EC 号】 | 206-442-2 |
| PubChem Substance ID【PubChem化学物质编号】 | 24896894 |
| Application【应用】 | 6-Methylmercaptopurine riboside (6MMPr) is used in studies on thiopurine metabolism by enzymes such as inosine-5′-monophosphate dehydrogenase and thiopurine methyltransferase. 6MMPr may also be used to study mechanisms of bovine viral diarrhea virus (BVDV) inhibition. 6-Methylmercaptopurine riboside (6MMPR) has been used as a phosphoribosyl pyrophosphate amidotransferase inhibitor to study its effects on DNA replication in a retinoblastoma (Rb) phosphorylation-independent manner in human cytomegalovirus (HCMV) , as a purine analog to determine its effects on angiogenesis of endothelial cells induced by fibroblast growth factor 2 (FGF2) in vitro and in vivo, as a metabolite of 6-methylmercaptopurine to determine its levels in human plasma by high-performance liquid chromatography (HPLC) method . |
| Biochem/physiol Actions【生化/生理作用】 | 6-Methylmercaptopurine riboside (6MMPR) is a modified thiopurine nucleoside involved in the inhibition of purine synthesis. It exhibits anti-viral effects against various viruses. 6MMPR is an analog of purine and an inhibitor of nerve growth factor-activated protein kinase N. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | synthetic (organic) |
| Assay【测定】 | ≥99% (HPLC) |
| form【形式】 | powder |
| solubility【溶解性】 | methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O[C@H]([C@@H](CO)O1)[C@@H](O)[C@@H]1N2C=NC3=C(SC)N=CN=C32 |
| InChI | 1S/C11H14N4O4S/c1-20-10-6-9(12-3-13-10)15(4-14-6)11-8(18)7(17)5(2-16)19-11/h3-5,7-8,11,16-18H,2H2,1H3 |
| InChI key | ZDRFDHHANOYUTE-UHFFFAOYSA-N |
| packaging【包装】 | 1 g in poly bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
