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A922500
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3336299 | 1 MG | 747 | |||
3336299 | 5 MG | 3110 |
产品别名
959122-11-3
A922500
基本信息
Empirical Formula【经验(实验)分子式】 | C26H24N2O4 |
Molecular weight | 428.48 |
NACRES | NA.77 |
Application【应用】 | A922500 has been used in the inhibition of diacylglycerol acyltransferase (DGAT) in epithelial human breast cancer cell line (MDA-MB-231), digitonin-permeabilized human cancer cells, human myotubes and macrophages. |
Biochem/physiol Actions【生化/生理作用】 | The diacylglycerol acyltransferase (DGAT) 1 inhibitor A922500 was shown to effectively reduce postprandial serum triglyceride levels in rodents at concentrations of 0.03, 0.3 and 3 mg/kg. These results suggest A922500 may have beneficial effects in reducing the risk of cardiovascular disease. Diacylglycerol acyltransferase (DGAT-1) inhibitor; IC50 7 to 24 nM |
Physical form【外形】 | A922500 is supplied as a crystalline solid. |
Preparation Note【制备说明】 | A stock solution may be made by dissolving the A922500 in the solvent of choice. A922500 is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF). |
产品性质
biological source【生物来源】 | synthetic (organic) |
Quality Level【质量水平】 | 100 |
Assay【测定】 | >95% (HPLC) |
form【形式】 | powder |
mol wt【分子量】 | Mw 428.5 |
solubility【溶解性】 | DMSO: 10 mg/mL, clear, colorless to greenish-yellow |
storage temp.【储存温度】 | −20℃ |
InChI key | BOZRFEQDOFSZBV-DHIUTWEWSA-N |
packaging【包装】 | 1, 5, 10 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |