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酰基酶Ⅰ 来源于猪肾脏

Acylase I from porcine kidney
产品编号:3338311
规格:Grade II, salt-free, lyophilized powder, 500-1,500 units/mg protein
CAS NO:9012-37-7
包装规格:1 G,10 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
33383111 G2810
333831110 G15140
产品别名

9012-37-7

酰基酶Ⅰ 来源于猪肾脏

Acylase I from porcine kidney

Aminoacylase

N-Acylamino acid amidohydrolase

N-酰基氨基酸酰胺水解酶

氨基酰化酶

基本信息
Enzyme Commission (EC) Number【酶学委员会(EC)编号】
3.5.1.14 ( BRENDA | IUBMB )
EC number【EC 号】
232-732-3
MDL number
MFCD00081285
NACRES
NA.54
Application【应用】
Acylase I from porcine kidney has been used to study the acylase I-catalyzed deacetylation of various S-alkyl-N-acetyl-L-cysteines and their carbon and oxygen analogues . Acylase I may be useful to catalyze N-acetyl amino acids to enantiomerically pure L-amino acids .
Biochem/physiol Actions【生化/生理作用】
Acylase I is a zinc metalloprotein that catalyzes the kinetic resolution of unnatural and rarely occurring α-amino acids. Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality. Acylase I catalyzes the deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. n-Butylmalonic acid is an inhibitor of acylase I. S-alkyl-N-acetyl-L-cysteines with short (C0-C3) and unbranched S-alkyl substituents have been found to be good acylase I substrates.
Unit Definition【单位定义】
One unit will hydrolyze 1.0 μmole of N-acetyl-L-methionine per hr at pH 7.0 at 25 ℃.
Analysis Note【分析说明】
Protein determined by biuret.
产品性质
Quality Level【质量水平】
200
type【类型】
Grade II
form【形式】
salt-free, lyophilized powder
Specific Activity
500-1,500 units/mg protein
UniProt accession no.【UniProt登记号】
P37111
storage temp.【储存温度】
−20℃
Gene Information
pig ... ACY1(396930)
packaging【包装】
1, 10 g in poly bottle
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H315 - H319 - H334 - H335
Precautionary Statements
P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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