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阿达帕林
Adapalene
| 产品编号： | 3338369 |
| 规格： | European Pharmacopoeia (EP) Reference Standard |
| CAS NO： | 106685-40-9 |
| 包装规格： |
| 产品类别： | 进口试剂 |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3338369 | 1720 |
产品别名
106685-40-9
阿达帕林
Adapalene
CD-271
6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic Acid
Differin
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C28H28O3 |
| Molecular weight | 412.52 |
| MDL number | MFCD03106112 |
| PubChem Substance ID【PubChem化学物质编号】 | 329831273 |
| NACRES | NA.24 |
| General description【一般描述】 | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. |
| Biochem/physiol Actions【生化/生理作用】 | Retinoic acid analogue that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro. Displays comedolytic activity. Its unique pharmacological properties make it superior to other retinoids for the treatment of acne. |
| Caution【注意】 | Please find SDS provided by EDQM here.. |
| Other Notes【其他说明】 | Sales restrictions may apply. |
产品性质
| grade【等级】 | pharmaceutical primary standard |
| manufacturer/tradename | EDQM |
| application(s) | pharmaceutical (small molecule) |
| format【格式】 | neat |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1ccc(cc1C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)-c5ccc6cc(ccc6c5)C(O)=O |
| InChI | 1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)/t17-,18+,19-,28- |
| InChI key | LZCDAPDGXCYOEH-AADAIPAGSA-N |
| packaging【包装】 | Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H361d |
| Precautionary Statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| Hazard Classifications【危险分类】 | Repr. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
