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Adenosine 5′-[β-thio]diphosphate trilithium salt

产品编号:3338458
规格:≥80% (HPLC)
CAS NO:73536-95-5
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
33384585 MG2980
333845825 MG8780
产品别名

73536-95-5

Adenosine 5′-[β-thio]diphosphate trilithium salt

Adenosine-5′-0-(2-thiodiphosphate) trilithium salt

Ado-5′-PP[S]

ADP-β-S

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C10H12Li3N5O9P2S
Molecular weight
461.07
MDL number
MFCD00077314
eCl@ss
32160414
PubChem Substance ID【PubChem化学物质编号】
24891307
NACRES
NA.77
Application【应用】
Adenosine 5′-[β-thio]diphosphate trilithium salt has been used to induce neuropathic pain in rats to study the effect of dorsal horn cannabinoid CB2 receptor activation on the expression of P2Y12 and P2Y13 (purinoceptors) receptors.
Adenosine 5′-[β-thio]diphosphate is a substrate and inhibitor for AMP dependent enzyme systems. Adenosine 5′-[β-thio]diphosphate has been used to explore the myenteric control mechanisms of human esophageal motility and the effect of nitrergic and nonnitrergic neurotransmitters.
Biochem/physiol Actions【生化/生理作用】
P2Y 受体激动剂。
Features and Benefits【特点和优势】
This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes【其他说明】
Non-hydrolyzable ADP analog
Substrates【底物】
Substrate and inhibitor for AMP dependent enzyme systems.
产品性质
Quality Level【质量水平】
200
Assay【测定】
≥80% (HPLC)
form【形式】
powder
storage temp.【储存温度】
−20℃
SMILES string
[Li+].[Li+].[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O
InChI
1S/C10H15N5O9P2S.3Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
InChI key
CPKFUAYUUSSFFZ-MSQVLRTGSA-K
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H371
Precautionary Statements
P301 + P312 + P330 - P308 + P311
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - STOT SE 2
Target Organs【靶器官】
Eyes
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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