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Almotriptan malate
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3339594 | 10 MG | 1530 | |||
| 3339594 | 50 MG | 5640 |
产品别名
181183-52-8
Almotriptan malate
PNU 180638
3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indole malate
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H25N3O2S · C4H6O5 |
| Molecular weight | 469.55 |
| NACRES | NA.77 |
| Application【应用】 | Almotriptan is a serotonin 5HT-1B/1D-receptor agonist; antimigraine. Almotriptan at an oral dose of 12.5 mg, is recommended to be safe for treating migraine. |
| Biochem/physiol Actions【生化/生理作用】 | Almotriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Almotriptan has low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower. Affinity for 5-HT(7) and 5-HT(1A) receptors was approximately 40 and 60 times lower than that for 5-HT(1B/1D) receptors, respectively. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 10 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9) |
| InChI key | QHATUKWEVNMHRY-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
