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Anti-ABL1/2 (Ab-393/429) antibody produced in rabbit
产品别名
Anti-ABL1/2 (Ab-393/429) antibody produced in rabbit
Anti-JTK7
Anti-c-ABL
Anti-ABL
Anti-v-abl
Anti-P150
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 135-210 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (D-T-Y-T-A) |
| NCBI accession no.【NCBI登记号】 | NM_001136000.2 NM_005157.3 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ABL1(25), ABL2(27) mouse ... ABL1(11350), ABL2(11352) |
基本信息
| General description【一般描述】 | The antibody detects endogenous levels of total ABL1/2 protein. |
| Immunogen【免疫原】 | Peptide sequence around aa. 391-395 (D-T-Y-T-A), according to the protein NP_005148.2, NP_001129472.1 |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品说明
| Target description【目标描述】 | Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
