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Anti-AIMP2 antibody produced in rabbit
产品别名
Anti-AIMP2 antibody produced in rabbit
JTV1
p38
JTV-1
基本信息
NACRES | NA.41 |
General description【一般描述】 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) is localized to the cytosol. It is part of the multi-tRNA synthetase complex. The AIMP2 gene is located on human chromosome 7. |
Specificity【特异性】 | The antibody detects endogenous levels of total AIMP2 protein. |
Immunogen【免疫原】 | Fusion protein corresponding to residues near the N terminal of human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 |
Biochem/physiol Actions【生化/生理作用】 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) is a scaffold protein which functions as a tumor suppressor. It stimulates the ubiquitin-mediated degradation of FUSE-binding protein (FUBP1), which is a transcription activator. AIMP2 activates tumor suppressor p53 and stimulates apoptosis. The assembly of macromolecular tRNA synthetase complex depends on AIMP2. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 35 kDa |
species reactivity | human |
concentration【浓度】 | 0.5 mg/mL |
technique(s) | immunohistochemistry: 1:10- 1:50 western blot: 1:200-1:1000 (Cell Lysate) |
isotype【同位素/亚型】 | IgG |
accession no.【登记号】 | NP_006294.2 |
UniProt accession no.【UniProt登记号】 | Q13155 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... AIMP2(7965) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 1 |