Anti-AP2M1 antibody produced in chicken

MFCD02262538

NA.41

AP2M1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human AP2M1.

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The action of this antibody can be blocked using blocking peptide SBP3500044.

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

chicken

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

rat, human, mouse

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NP_004059

Q96CW1

dry ice

−20℃

human ... AP2M1(1173)

The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.

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12 - Non Combustible Liquids

WGK 2