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Anti-ARHGEF10 antibody produced in rabbit
产品别名
Anti-ARHGEF10 antibody produced in rabbit
Rho guanine nucleotide exchange factor 10
ARHGEF10
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-ARHGEF10 Antibody detects endogenous levels of total ARHGEF10 protein. The gene ARHGEF10 (Rho guanine nucleotide exchange factor 10) is mapped to human chromosome 8p23. It belongs to the Rho-specific guanine nucleotide exchange factor family. The protein contains tandem Dbl homology (DH) domain, pleckstrin homology (PH) domain and putative transmembrane domains. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human ARHGEF10. Immunogen Range: 339-388 |
| Biochem/physiol Actions【生化/生理作用】 | ARHGEF10 (Rho guanine nucleotide exchange factor 10) works as a guanine nucleotide exchange factor for RhoA, RhoB and RhoC. It is involved in atherosclerotic cerebral infarction and mutation in ARHGEF10 is associated with increased risk of atherothrombotic stroke. Mutation in ARFGEF10 is also linked with slowed nerve conduction velocities and thin myelination of peripheral nerves. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 151 kDa |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | O15013 |
| UniProt accession no.【UniProt登记号】 | O15013 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ARHGEF10(9639) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
