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ANTI-ASB10(N-TERMINAL) antibody produced in rabbit
| 产品编号： | 3346250 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 400 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
ANTI-ASB10(N-TERMINAL) antibody produced in rabbit
ASB10
Ankyrin repeat and SOCS box protein 10
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | ASB10 belongs to the ankyrin repeat and SOCS box (ASB) family and the suppressor of cytokine signaling (SOCS) box protein superfamily. It consists of a number of ankyrin (ANK) repeat protein domains and a C-terminal suppressor of cytokine signaling (SOCS) box. Depending on the number of ankyrin (ANK) repeat protein domains, ASB family is divided into 1-18 types. ASB10 is composed of seven ANK repeat domains and a SOCS box at the C-terminus end. |
| Application【应用】 | ANTI-ASB10(N-TERMINAL) antibody produced in rabbit is suitable for western blot at a dilution of 1:1000. |
| Biochem/physiol Actions【生化/生理作用】 | ASB10 (ankyrin repeat and SOCS box containing 10) plays a vital role in the ubiquitination-mediated proteasomal and autophagy-lysosomal degradation pathways. The ANK repeat containing domain is responsible for protein-protein interactions whereas the SOCS (suppressor of cytokine signaling) box motif helps in ubiquitination of the protein by binding to the multisubunit E3 ubiquitin ligase complex. ASB family interacts specifically with Cul5-Rbx2 in cells to form an E3 ubiquitin (Ub) ligase complex. |
| Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 50894 Da |
| species reactivity | human |
| technique(s) | western blot: 1:1000 |
| NCBI accession no.【NCBI登记号】 | NP_001135931.2 |
| UniProt accession no.【UniProt登记号】 | Q8WXI3 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ASB10(136371) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
