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Anti-Atg101 antibody produced in rabbit
产品别名
Anti-Atg101 antibody produced in rabbit
Anti-Atg13-interacting protein
Anti-C12orf44
Anti-autophagy-related protein 101
Anti-chromosome 12 open reading frame 44
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Autophagy101 (Atg101) is located on the human chromosome at 12q13.13. |
| Application【应用】 | Anti-Atg101 antibody has been used in
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| Biochem/physiol Actions【生化/生理作用】 | Autophagy101 (Atg101) is a mammalian Autophagy13 (Atg13) binding protein essential for autophagy. Atg13 forms a stable complex with ULK1 (Serine/threonine-protein kinase ULK1) and FIP200 (FAK family kinase-interacting protein of 200 kDa). Atg101 associates with the ULK1-Atg13- FIP200 complex through direct interaction with Atg13. Mammalian target of rapamycin (mTOR) interacts with the ULK1-Atg13-FIP200 complex in a nutrient dependent manner, suggesting that mTOR regulates autophagy through this complex. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~30 kDa |
| species reactivity | human |
| concentration【浓度】 | ~1.0 mg/mL |
| technique(s) | western blot: 0.25-0.5 μg/mL using whole extracts of HEK-293T cells over expressing human Atg101 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... C12orf44(60673) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
