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Anti-BACE2 (ab1) antibody produced in rabbit
| 产品编号： | 3347278 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-BACE2 (ab1) antibody produced in rabbit
Anti-Asp2
Anti-β-site APP-cleaving enzyme 2
基本信息
| MDL number | MFCD03454780 |
| NACRES | NA.41 |
| General description【一般描述】 | β-site amyloid precursor protein- cleaving enzyme 2 (BACE2) is a glycoprotein which is part of the transmembrane aspartic protease family. The gene encoding this protein is localized on human chromosome 21q22.3. |
| Immunogen【免疫原】 | a synthetic peptide corresponding to amino acids 44-59 of human BACE2. |
| Biochem/physiol Actions【生化/生理作用】 | β-site amyloid precursor protein- cleaving enzyme 2 (BACE2) has a role in the non-amyloidogenic processing of amyloid precursor protein. It also possesses an amyloid β-degrading protease activity. Cells of individuals with Down′s syndrome show an enhanced expression of BACE1 mRNA and the protein. |
| Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP2247. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | predicted mol wt 57 kDa |
| species reactivity | human, mouse, rat |
| technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9Y5Z0 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BACE2(25825) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
